Eguski Soluciones Integradas S.L. | Longitudinal relationship certainly one of coronary artery calcification, serum phosphorus, and kidney function
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Longitudinal relationship certainly one of coronary artery calcification, serum phosphorus, and kidney function

Longitudinal relationship certainly one of coronary artery calcification, serum phosphorus, and kidney function

Longitudinal relationship certainly one of coronary artery calcification, serum phosphorus, and kidney function

18. O’Seaghdha CM, Hwang SJ, Muntner P, Melamed ML, Fox CS. Gel phosphorus predicts experience persistent renal situation and you can prevent-stage kidney condition. Nephrol Switch Transplant. 2011;26(9):2885-2890. (PubMed)

19. Foley Registered nurse, Collins AJ, Herzog Ca, Ishani A good, Kalra PA. Gel phosphate and you may kept ventricular hypertrophy in young people: the newest coronary artery risk growth in young adults analysis. Renal Bloodstream Force Res. 2009;32(1):37-forty two. (PubMed)

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twenty two. de Boer IH, Rue TC, Kestenbaum B. Serum phosphorus concentrations about third Federal Health and Nourishment Test Survey (NHANES III). In the morning J Renal Dis. 2009;53(3):399-407. (PubMed)

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twenty five. Palmer Sc, Hayen Good, Macaskill P, ainsi que al. Gel quantities of phosphorus, parathyroid hormone, and you may calcium supplements and you can dangers of demise and you can cardiovascular disease inside the someone having persistent renal problem: a systematic remark and you can meta-study. JAMA. 2011;305(11):1119-1127. (PubMed)

twenty seven. Hruska KA, Mathew S, Lund Roentgen, Qiu P, Pratt R. Hyperphosphatemia regarding persistent renal state. Renal Int. 2008;74(2):148-157. (PubMed)

twenty eight. Jono S, McKee MD, Murry Ce, ainsi que al. Phosphate control out of vascular smooth muscles mobile calcification. Circ Res. 2000;87(7):E10-17. (PubMed)

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31. Chang AR, Lazo Meters, Appel LJ, Gutierrez OM, Grams Myself. Large fat loss phosphorus consumption try on the the-trigger mortality: comes from NHANES III. Was J Clin Nutr. 2014;99(2):320-327. (PubMed)

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Effects of intercourse and you can postmenopausal estrogen have fun with for the gel phosphorus account: a cross-sectional examination of the newest National Health insurance and Diet Examination Survey (NHANES) 2003-2006

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Phosphorus homeostasis is firmly controlled by PTH/nutritional D/FGF-23 axis from inside the those with regular renal setting (look for Control). Improved hormonal out of PTH and you will FGF-23 assists in maintaining phosphorus serum concentrations throughout the regular diversity (dos.5-cuatro.5 milligrams/dL) inside the background out of higher phosphorus intake (9). That it causes solution phosphorus getting simply weakly coordinated to help you phosphorus usage (22). From note, sustained develops when you look at the FGF-23 and you can PTH are commonly seen during the CKD so you’re able to look after regular gel phosphorus density even with a decrease in urinary phosphorus excretion (23). Increased FGF-23, rather than gel phosphorus, seems to be an earlier marker away from disordered phosphorus homeostasis and you will a good predictor regarding bad health consequences for the people that have very early-stage CKD (23, 24). Hence, it’s reasonable to imagine you to definitely measuring solution phosphorus in the people with typical renal mode you should never effectively reflect early disturbances from inside the phosphorus metabolic process on account of highest phosphorus application.

A corner-sectional study held in 2,344 Brazilian everyone (median decades, 58 decades) displayed a link between higher phosphorus consumption and you will enhanced chance of crack. But really, consumption out-of almost every other nutritional supplements relevant to bone fitness, particularly calcium, magnesium, and you can supplement D, were beneath the RDA inside people, while phosphorus consumption was indeed near the RDA (35). Although it seems that hormones and calcium conditions will be eliminated because of the a sufficient calcium supplements-to-phosphorus intake ratio, there is absolutely no persuading evidence your dietary phosphorus profile knowledgeable in the usa negatively apply to bones mineral occurrence. Nevertheless, the newest replacing out of phosphate-that has had sodas and you can snacks having milk or other calcium supplements-rich dinner can get show a significant chance to help you limbs wellness (see the post on Calcium supplements) (36).

17. Tonelli Meters, Sacks F, Pfeffer M, et al. Loved ones between serum phosphate level and you may cardio knowledge speed when you look at the some body which have coronary disease. Flow. 2005;112(17):2627-2633. (PubMed)

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